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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA5
All Species:
24.85
Human Site:
T465
Identified Species:
36.44
UniProt:
O75582
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75582
NP_004746.2
802
89865
T465
S
K
R
M
E
A
N
T
Q
K
E
I
T
A
L
Chimpanzee
Pan troglodytes
XP_001140389
894
100719
T557
S
K
R
M
E
A
N
T
Q
K
E
I
T
A
L
Rhesus Macaque
Macaca mulatta
XP_001088246
1054
117436
T717
S
K
R
M
E
A
N
T
Q
K
E
I
T
A
L
Dog
Lupus familis
XP_547953
806
90703
T472
S
K
R
M
E
A
N
T
Q
K
E
I
T
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
T450
S
R
R
L
E
E
N
T
Q
R
E
V
A
A
L
Rat
Rattus norvegicus
Q63531
735
82865
Y418
N
L
V
F
S
D
G
Y
I
V
K
E
T
I
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
K400
E
G
H
P
N
I
V
K
L
H
E
V
Y
H
D
Chicken
Gallus gallus
Q5F3L1
789
89022
T455
S
K
R
M
E
A
N
T
Q
R
E
I
T
A
L
Frog
Xenopus laevis
P10665
733
82620
S426
R
E
T
I
G
V
G
S
Y
S
V
C
K
R
C
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
S430
K
E
D
I
G
V
G
S
Y
S
I
C
K
R
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
D673
A
L
I
S
C
A
L
D
T
T
N
H
K
N
I
Honey Bee
Apis mellifera
XP_395099
910
102507
R490
S
R
R
I
D
C
G
R
E
A
S
L
L
R
S
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
A421
S
Q
K
F
A
S
Q
A
Q
R
E
A
R
I
L
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
Q424
S
R
R
V
A
C
T
Q
E
I
T
T
L
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
K179
R
K
D
K
I
V
E
K
N
H
A
E
Y
M
K
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
E385
A
Y
I
V
S
K
C
E
V
T
H
T
L
A
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
75
93.1
N.A.
62.8
41
N.A.
82.1
89.4
40
40.5
N.A.
28.5
45.7
46.8
53.3
Protein Similarity:
100
88.5
75.1
95.1
N.A.
76.6
57.9
N.A.
86.1
94.6
57.4
57.3
N.A.
40
62.3
63
66.2
P-Site Identity:
100
100
100
100
N.A.
60
6.6
N.A.
6.6
93.3
0
0
N.A.
6.6
13.3
26.6
20
P-Site Similarity:
100
100
100
100
N.A.
86.6
20
N.A.
13.3
100
20
20
N.A.
20
46.6
53.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
0
13
38
0
7
0
7
7
7
7
44
0
% A
% Cys:
0
0
0
0
7
13
7
0
0
0
0
13
0
0
13
% C
% Asp:
0
0
13
0
7
7
0
7
0
0
0
0
0
0
7
% D
% Glu:
7
13
0
0
38
7
7
7
13
0
50
13
0
0
7
% E
% Phe:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
0
13
0
25
0
0
0
0
0
0
0
7
% G
% His:
0
0
7
0
0
0
0
0
0
13
7
7
0
7
0
% H
% Ile:
0
0
13
19
7
7
0
0
7
7
7
32
0
13
7
% I
% Lys:
7
38
7
7
0
7
0
13
0
25
7
0
19
0
7
% K
% Leu:
0
13
0
7
0
0
7
0
7
0
0
7
19
0
50
% L
% Met:
0
0
0
32
0
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
7
0
0
0
7
0
38
0
7
0
7
0
0
7
0
% N
% Pro:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
0
0
7
7
44
0
0
0
0
7
0
% Q
% Arg:
13
19
50
0
0
0
0
7
0
19
0
0
7
19
0
% R
% Ser:
57
0
0
7
13
7
0
13
0
13
7
0
0
0
7
% S
% Thr:
0
0
7
0
0
0
7
38
7
13
7
13
38
0
0
% T
% Val:
0
0
7
13
0
19
7
0
7
7
7
13
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
7
13
0
0
0
13
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _